Thermodynamic and kinetic studies are essential to both establishing a solid practical understanding of molecular mechanisms and to the thorough design of translational studies such as drug development and identification of therapeutic targets. Molecular association/dissociation ratios provide invaluable information on the binding mechanisms, formation, and stability of biologically relevant complexes such as ligand-receptor or small molecule drug-target complexes.

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On the other hand, evaluation of drug or protein affinity to a target is crucial for effective decision-making in the drug development pipeline. Therefore, employing kinetic or thermodynamic studies is crucial to extracting information on the binding affinities and association/dissociation rates of biomolecular interactions to encourage optimal drug screening and candidate selection.